| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2025 , Vol 63 , Num 2
Cardioprotective potential of Cucurbita maxima seeds and its active fractions
1 Bharati Vidyapeeth?s College of Pharmacy, Department of Pharmacology, C.B.D. Belapur, Navi Mumbai, IndiaDOI : 10.23893/1307-2080.APS6321 Viewed : 3454 - Downloaded : 1183 The current study"s goal was to assess the cardiovascular impact of Cucurbita maxima (CM) seed"s hydroalcoholic extract and, its ethyl acetate and n-butanol fractions, for potential usage in myocardial infarction. All of the resulting extracts underwent qualitative screening using techniques like High Performance Thin Layer Chromatography (HPTLC), Fourier Transform Infrared Spectroscopy (FTIR), and UV Visible Spectroscopy. In vitro studies revealed that the crude extract and fractions of Cucurbita maxima seeds have total antioxidant and free radical scavenging properties. The Chick Chorioallantoic Membrane Assay (CAM), an in ovo assay, was used to assess the cardiovascular activity of the crude extract and its fractions. The study illustrated the findings by demonstrating the angiogenic impact, which indicated desired cardiovascular activity in the CAM Assay. Keywords : Cucurbita maxima, HPTLC, antioxidant activity, fractionation, chick chorioallantoic membrane assay