| Acceptance rate | 46% |
|---|---|
| Time to first decision | 20 days* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2023 , Vol 61 , Num 4
Antibacterial and anthelmintic effect of the combination of pomegranate peel and olive leaf extracts
1 Department of Pharmaceutical Technology, Faculty of Pharmacy, Istinye University, Istanbul, Türkiye2 Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Istinye University, Istanbul, Türkiye
3 Department of Pharmacognosy, Faculty of Pharmacy, Istinye University, Istanbul, Türkiye
4 Department of History and Deontology of Pharmacy, Faculty of Pharmacy, Istinye University, Istanbul, Türkiye
5 Department of Medical Biochemistry, Faculty of Medicine, Istinye University, Istanbul, Türkiye
DOI : 10.23893/1307-2080.APS6124 Pomegranate peel and olive leaf are known to have antibacterial activity. These two plants have been studied in various studies. However, there is no study on the synergistic effect of these two plants. In this study, the antibacterial activity of a supplement containing pomegranate peel and olive leaf extracts against S. mutans and its antihelmintic activity against C. elegans were determined. Results obtained by the disk diffusion method and microdilution test are 12.5 mm and ? 1024 ?g/ mL, respectively. Anthelmintic activity experiments revealed that the lifespan of worms was shortened as a result of the synergistic effect of the extracts. Our results revealed the synergistic effect of these two extracts against the microbes and possible helminths in the oral flora. Increasing antibiotic resistance has led researchers to work on the detection of new plant extracts and substances. It is aimed that this study on plant extracts will help future studies. Keywords : Pomegranate peel, olive leaves, antibacterial, antihelmintic, C. elegans