ACTA Pharmaceutica Sciencia
2005 , Vol 47 , Num 2
LC-MS ANALYSIS OF CORMS OF COLCHICUM HIEROSOLYMITANUM (COLCHICACEAE)
Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan
LC-MS analysis of corms of Colchicum hierosolymitanum Feinbr (Colchicaceae) was conducted using a single quadrupole mass analyzer equipped with (+)-APCI ionizing interface. (-)-Colchicine (7) and eight (1-6, 8, 9) natural analogues were detected and identified in the alkaloid rich fraction. These compounds are reported for the first time in C. hierosolymitanum.
Keywords :
(-)-COLCHICINE; C HIEROSOLYMITANUM; (+)-APCI LC-MS; JORDAN