| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2019 , Vol 57 , Num 1
Biosynthesis, Characterization and Cytotoxicity of Zinc Nanoparticles Using Panax ginseng Roots, Araliaceae
1 Ministry of Education, Department of Heet Education, Hit, Iraq2 University Of Anbar, Department of Ecology, College of Applied Sciences-Hit, Hit, Anbar, Iraq
DOI : 10.23893/1307-2080.APS.05702 Viewed : 21125 - Downloaded : 7093 This study aims to biosynthesize zinc nanoparticles from the aqueous extract of Panax ginseng (Red Ginseng) roots. The characteristics of ZnNPs were checked using change in color, UV-Vis, SEM, SPM, AFM, FT-IR, and EDS analyses, and assessed their cytotoxicity against L20B tumor cell line using MTT assay. The change in the solution color after 3 hr on 70 °C is from yellow to the brownish color with whitish sediments. The adsorption peak of UV-vis is 340 nm as evidence of formation the Zn nanoparticles. AFM, SEM and EDS observe shapes of zinc nanoparticles which are spherical to irregular particles with rate of size 59.76 nm. The concentration 100% Zinc nanoparticles significantly (p<0.01) recorded best inhibition percentage 41.70% against murine fibroblast cells (L20B) which have receptors of human polioviruses. Thus, this work is considered as an auspicious first test to reduce the growth of cancers using green ZnNPs of Ginseng (Panax ginseng) in vitro. Keywords : Anticancer activity, EDS, Red Ginseng, SPM, ZnNPs