| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2025 , Vol 63 , Num 2
Cardioprotective potential of Cucurbita maxima seeds and its active fractions
1 Bharati Vidyapeeth?s College of Pharmacy, Department of Pharmacology, C.B.D. Belapur, Navi Mumbai, IndiaDOI : 10.23893/1307-2080.APS6321 Viewed : 80 - Downloaded : 23 The current study"s goal was to assess the cardiovascular impact of Cucurbita maxima (CM) seed"s hydroalcoholic extract and, its ethyl acetate and n-butanol fractions, for potential usage in myocardial infarction. All of the resulting extracts underwent qualitative screening using techniques like High Performance Thin Layer Chromatography (HPTLC), Fourier Transform Infrared Spectroscopy (FTIR), and UV Visible Spectroscopy. In vitro studies revealed that the crude extract and fractions of Cucurbita maxima seeds have total antioxidant and free radical scavenging properties. The Chick Chorioallantoic Membrane Assay (CAM), an in ovo assay, was used to assess the cardiovascular activity of the crude extract and its fractions. The study illustrated the findings by demonstrating the angiogenic impact, which indicated desired cardiovascular activity in the CAM Assay. Keywords : Cucurbita maxima, HPTLC, antioxidant activity, fractionation, chick chorioallantoic membrane assay