Acceptance rate 46%
Time to first decision 6 months*
Time to decision with review 50 days*

*Approximate number of days

**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.


ACTA Pharmaceutica Sciencia 2023 , Vol 61 , Num 3
Biological activity and chemical composition of the essential oil from the fruits of Ferula rigidula Fisch. ex DC.
Gökalp İŞCAN 1 Mine KÜRKÇÜOĞLU 1 Fatma TOSUN 2 Mahmut MİSKİ 3
1 Anadolu University, Faculty of Pharmacy, Department of Pharmacognosy, Eskisehir, Türkiye
2 Istanbul Medipol University, School of Pharmacy, Department of Pharmacognosy, Istanbul, Türkiye
3 Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy, Istanbul, Türkiye
DOI : 10.23893/1307-2080.APS6117 Viewed : 6617 - Downloaded : 1575 The hydro-distilled essential oils of the fruits of F. rigidula Fisch. ex DC. was analyzed by Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) systems at the same time. Thirty-one compounds were characterized representing 98.2% of the essential oils. The main components of the oil were determined as a-pinene and camphene (24% and 20%, respectively). The anticandidal and antibacterial effects of the essential oil were determined by using partly modified CLSI protocols M27-A2 and M7-A7, respectively. The essential oil of the dried fruits showed several inhibitory effects on the tested bacteria panel (MIC, 62.5 to 2000 µg/mL) and Candida species (MIC, 125 to 1000 µg/mL). Keywords : Antibacterial; anticandidal; Ferula rigidula ;essential oil; GCMS

Istanbul Medipol University