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ACTA Pharmaceutica Sciencia
2026 , Vol 64 , Num 1
The relationship between inflammatory bowel disease severity and quality of life of Iraqi patients
1 University of Baghdad, School of Pharmacy, Department of Clinical Pharmacy, Baghdad, Iraq2 Ministry of Health and Environment, Medical City, The Gastroenterology and Hepatology Teaching Hospital, Baghdad, Iraq
DOI : 10.23893/1307-2080.APS6403 Viewed : 296 - Downloaded : 94 Inflammatory bowel disease (IBD), significantly impacts patients" quality of life (QoL) due to its chronic, relapsing nature and associated physical and psychological burdens. This cross-sectional study aimed to investigate the relationship between IBD severity and QoL among Iraqi patients in100 IBD patients recruited from The Gastroenterology and Hepatology Teaching Hospital, Medical City, Baghdad, Iraq between December 2024 and February 2025. QoL was assessed using validated Arabic WHOQOL-BREF questionnaire, covering physical, psychological, social, and environmental domains, alongside ESR as a measure of IBD severity. Results revealed that self-perceived QoL (3.79 vs. 3.19, p=0.002), health satisfaction (3.83 vs. 3.23, p=0.012), and psychological domain scores (22.58 vs. 21.35, p=0.017) were significantly lower in patients with elevated ESR compared to those with normal ESR. However, physical, social, and environmental domains showed no significant differences. Demographic factors such as sex, residence and marital status had minimal impact on QoL, except for higher self-perceived QoL in single versus married patients (3.75 vs. 3.16, p=0.002). The findings underscore that active inflammation predominantly affects psychological wellbeing and subjective health perceptions in IBD patients. This study highlights the importance of integrating psychosocial support into IBD management. Keywords : inflammatory bowel disease, quality of life, ESR, biomarkers, Iraq