| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2024 , Vol 62 , Num 4
Topical mupirocin-steroid for wound care in an era of rising antibiotic resistance
1 Al-Kut University College, Department of Pharmacy, 52001-Wasit, Iraq2 Wasit University, College of Engineering, Civil Engineering Department, Iraq
DOI : 10.23893/1307-2080.APS6257 Viewed : 162 - Downloaded : 40 Wound infections are characterized by antibiotic-resistant bacteria, a growing issue. When these microbes infect a wound, it"s treated aggressively. A few therapeutic antibiotics make this therapy problematic. Mupirocin and other newly discovered methods show promise as bacterial wound-killing agents. This study includes three topical mupirocin-steroid therapies that were tested for their ability to treat antibiotic-resistant clinical isolates. Wounds may be treated using mupirocin-based liquid, cream, and dressing coating. The reduction in viable bacterial population after mupirocin exposure was used to compare the bactericidal efficiency of different mupirocin treatments. Results showed that each ingredient had the potential to reduce germ reproduction. The mupirocin-coated bandage was the most efficient strategy to kill antibiotic- resistant bacteria, whereas the liquid mupirocin was the least efficient. The mupirocin-coated steroid bandage swiftly killed the tested germs and showed promise against other bacterial strains. Mupirocin might be a therapeutic and prophylactic medication for wound colonization by organisms that hinder healing. Keywords : mupirocin, wound care, antibiotic resistance