| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2022 , Vol 60 , Num 3
Potent colon cancer cell line toxicity of the fruit extracts of Heptaptera triquetra (Vent.) Tutin
1 Department of Pharmacognosy, School of Pharmacy, Istanbul Medipol University, Istanbul, Turkey2 Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey
DOI : 10.23893/1307-2080.APS.6019 Viewed : 9443 - Downloaded : 2215 Cytotoxic activities of the fruit extracts of Heptaptera triquetra (Vent.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the fruits of H. triquetra showed the highest cytotoxic activities with IC50 values of 9.3 and 5.3 ug/mL on the COLO205 and KM12 cell lines, respectively. Whereas, the ethyl acetate extract of the fruits showed moderate cytotoxic activity with IC50 values of 22.3 ug/mL against the KM12 cell lines. Keywords : Cytotoxic activity, Heptaptera triquetra, Apiaceae