| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
2 Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
3 Centre for Nanomedicine and Biophysical Drug Delivery, National Institute for Pharmaceutical Research and Development, Abuja, Nigeria
4 Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria
DOI : 10.23893/1307-2080.APS.05725 Viewed : 14696 - Downloaded : 5262 A study has been made on the formulation and evaluation of Acetylsalicylic acid (ASA) suppositories using Goat fat (GF) and its binary blends with Palm Kernel oil and Liquid Paraffin.
Cocoa butter was used as the standard reference suppository base. Rectal suppositories containing ASA (300 mg) in pre-calibrated mould were prepared by fusion method and evaluated for appearance, crushing strength, weight variation, melting point, liquefaction time, content uniformity and in-vitro release using standard procedures.
Liquefaction or disintegration time (minutes) followed this order: ACB(4.40±0.84)
The foregoing indicates that GL or GP has promising potential and could be a substitute
suppository base in the formulation of ASA suppositories.