| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2016 , Vol 54 , Num 1
Beneficial Effects of Commonly Used Phytochemicals in Diabetes Mellitus
1 Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, 06100, Ankara, Turkey2 Çukurova University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, 01330, Adana, Turkey
3 Ankara University, Faculty of Pharmacy, Department of Pharmacology, 06100, Ankara, Turkey
4 Hacettepe University, Faculty of Pharmacy, Department of Pharmacognosy, 06100, Ankara, Turkey
DOI : 10.23893/1307-2080.APS.0541 Viewed : 14967 - Downloaded : 5466 Diabetes mellitus, a metabolic disorder, is characterized by absolute or relative deficiencies in insulin secretion and/or insulin action associated with chronic hyperglycemia. The prevalence of diabetes is increasing worldwide, especially in developing countries. The diabetes treatment has higher costs, limited efficacy and side effects. As a result of these factors, patients often have used alternative forms of therapy such as herbal medicines. Plants often contain various amounts of phenolics, flavonoids and tannins and most of the studies are focused on the antidiabetic effects of these phytochemicals due to their antioxidant properties. In this review, the role of oxidative stress on diabetes and the effects of different phytochemicals (limonene, sinnamic acid and ursolic acid) to diabetes mellitus therapy will be discussed. Keywords : limonene, cinnamic acid, ursolic acid, diabetes