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ACTA Pharmaceutica Sciencia
2010 , Vol 52 , Num 4
SYNTHESIS AND IN VITRO ANTIMICROBIAL ACTIVITY OF SOME NOVEL CHALCONES CONTAINING 5-PHENYL TETRAZOLE
Department of Pharmaceutical Chemistry, MES College of Pharmacy, Sonai, Ahmednagar, India
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5-phenyl 1-acetyl tetrazole were allowed to react separately with different aromatic aldehydes in presence of alkaline medium to yield corresponding 5-phenyl tetrazole 1- substituted chalcones. The compounds were identified by spectral data and screened evaluated for in vitro antimicrobial and antifungal activity.
Keywords :
5-PHENYL TETRAZOLE, CHALCONE, ANTI-MICROBIAL ACTIVITY