| Acceptance rate | 46% |
|---|---|
| Time to first decision | 6 months* |
| Time to decision with review | 50 days* |
*Approximate number of days
**The days mentioned above are averages and do not indicate exact durations. The process may vary for each article.
ACTA Pharmaceutica Sciencia
2009 , Vol 51 , Num 1
COMPARATIVE EFFICACY OF FOUR AYURVEDIC ANTIDIABETIC FORMULATIONS IN ALLOXAN-INDUCED DIABETIC RABBITS
Department of Pharmacology, V.L. College of Pharmacy, RAICHUR-584 103 (India)
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A number of polyherbal formulations are widely marketed claiming to be very effective in diabetes and other associated diseases. But, the documented reports authenticate that, though there are numerous traditional plants reported to have hypoglycemic properties, many of them proved to be not very effective in lowering blood glucose levels in severe diabetes. Emphasizing these perplexing reports, present study was planned to evaluate the efficacy of four ayurvedic antidiabetic formulations for their antihyperglycemic and antihyperlipidemic effects in alloxan-induced diabetic rabbits. Out of four formulations (A, B, C and D) studied formulation- A exhibited extremely significant antihyperglycemic activity for satisfactory duration and also showed a significant activity as an antihyperlipidemic agent compared to other three and tolbutamide. This study provides a ready reference for the selection of an appropriate formulation in the clinical practice and hence effective rational therapy; the overall theme of health sciences.
Keywords :
ANTIHYPERGLYCEMIC, ANTIHYPERLIPIDEMIC, AYURVEDIC FORMULATION, DIABETES, EFFICACY, SERUM LIPIDS