| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2026 , Vol 64 , Num 4
Investigation of the antimicrobial and cytotoxic effects of Viscum album (mistletoe) extracts
1 Istanbul University-Cerrahpaşa, Faculty of Veterinary Medicine, Department of Microbiology, Istanbul, Türkiye2 Istanbul University-Cerrahpaşa, Faculty of Veterinary Medicine, Department of Pharmacology and Toxicology, Istanbul, Türkiye
DOI : 10.23893/1307-2080.APS64027 Viewed : 57 - Downloaded : 40 The increasing resistance to antibiotics in the fight against infections, coupled with the rising incidence of cancer, has intensified interest in investigating plant-based antimicrobial agents with potential anticancer properties. Viscum album (mistletoe), which parasitizes host trees, has anticancer, anti-inflammatory, immunomodulatory, antiviral and antimicrobial effects. The toxicity of the active substances in different V. album samples depends on the type of host tree and the geographical location of the plant. This study investigated the in vitro antimicrobial properties of ethanolic, and aqueous extracts derived from the leaves and stems of V. album on specific bacterial and fungal species, as well as their cytotoxic potential on cancer cells. The findings revealed that these extracts demonstrated differing levels of antibacterial effects against multiple Gram-positive and Gram-negative bacterial species. Notably, the V. album ethanolic stem extracts were found to have a stronger inhibitory effect on B. subtilis (1.2 mg/mL) and B. cereus (2.4 mg/mL) compared to other extracts. Furthermore, V. album extracts were found to exhibit cytotoxic effects against HeLa cells. Based on these findings, the natural components contained in the V. album plant may represent a potential source of antimicrobial and anticancer agents. Unlike previous studies, this work provides a comparative evaluation of solvent- and tissue-dependent biological activity profiles of V. album extracts obtained from a single host species. Keywords : antimicrobial, antifungal, HeLa cells, cytotoxic effect, Viscum album (mistletoe)