| Submission to first decision
(The average time from manuscript submission to desk rejection, direct rejection/acceptance or assignment to the first editor) Note: For manuscripts that fully comply with the journal template. However, this timeframe does not apply to manuscripts with formatting or guideline deficiencies. If a manuscript is returned to the authors for corrections, the administrative review process will restart from the re-submission date. |
3 weeks |
|---|---|
| Submission to decision after review (For papers that are sent to review, the average time from submission to receipt of first editor decision) | 6 weeks |
| Submission to final decision (The average time from manuscript submission to the final editorial decision) | 16 weeks |
| Submission to publication (The average time from acceptance to publication. Manuscript published in early view are also included in this calculation) | 24 weeks |
ACTA Pharmaceutica Sciencia
2026 , Vol 64 , Num 3
In vitro assessment of serotonin bioaccessibility from foods and supplements in male reproductive health
1 Istanbul Sabahattin Zaim University, Department of Molecular Biology and Genetics, Istanbul, Türkiye2 Istanbul Sabahattin Zaim University, Department of Nutrition and Dietetics, Istanbul, Türkiye
DOI : 10.23893/1307-2080.APS64020 Viewed : 1095 - Downloaded : 503 Serotonin, a nutrient component, has been found to positively influence sperm motility and spermatogenic processes. In this study, the digestion and bioaccessibility of serotonin-rich foods, including 10 different foods and a serotonin supplement, were examined through in vitro models. The experiment was conducted using in vitro digestion models, and the obtained data were analyzed using the HPLC method. The serotonin content varied between 205 µg/100 g to 5.8 µg/100 g before digestion and 294.3 µg/100 g to 14 µg/100 g after digestion, while the bioaccessibility ranged from 1101% to 8%. The findings showed that most food samples had high serotonin bioaccessibility and that the serotonin levels varied before and after digestion. Most food samples showed serotonin bioaccessibility to be above 100%. The findings demonstrated that most food samples had high serotonin bioaccessibility and that the amount of serotonin varied before and after digestion. Keywords : infertility, serotonin, in vitro human digestion, HPLC