ACTA Pharmaceutica Sciencia 2021 , Vol 59 , Num 1
Antioxidant Properties of Capsule Dosage Form From Mixed Extracts of Garcinia Mangostana Rind and Solanum Lycopersicum Fruit
Mahalul Azam 1 Willy Tirza Eden 2 Arulita Ika Fibriana 1 Sri Ratna Rahayu 1
1 Public Health Department, Faculty of Sport Science, Universitas Negeri Semarang, Indonesia
2 Chemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Semarang, Indonesia
DOI : 10.23893/1307-2080.APS.05904 Several studies showed both Garcinia mangostana L. and Solanum lycopersicum L. have shown important role as natural sources of antioxidant compounds. Hence, capsule supplement from mixed extracts of Garcinia mangostana L. and Solanum lycopersicum L. was prepared. This study aims to investigate the antioxidant properties from the capsules supplement contained with mixed extracts of Garcinia mangostana rind (GMR) and Solanum lycopersicum fruit (SLF). Antioxidant activity of capsule dosage form was measured using DPPH, ABTS, and FRAP assays. In addition, the total phenolic content and total flavonoid content of the capsules preparation were also evaluated. Total phenolic content was 0.7082 ± 0.1372 mg GAE/capsule and total flavonoid content was 11.7769 ± 3.9504 µg QE/capsule. The strong correlation observed between antioxidant capacity by ABTS method and the total phenolic contents (R2= 0.995, P<0.05) indicated that phenolic compounds in capsule preparation related with its antioxidant activity. Keywords : Antioxidant, DPPH, ABTS, FRAP, Garcinia mangostana, Solanum lycopersicum

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