ACTA Pharmaceutica Sciencia 2011 , Vol 53 , Num 4
STUDIES ON ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF URTICA DIOICA L.
SEVDA SÜZGEÇ-SELÇUK, PETER J HOUGHTON
Marmara University, Faculty of Pharmacy, Department of Pharmacognosy, Istanbul, Turkey In this study, aerial parts of Urtica dioica L. have been assesed for antioxidant activity and antimicrobial activity. Antioxidant activity was done according to the liposome TBA method. Antimicrobial activity was done according to the serial dilution method. The ethanol extract of the aerial parts of U. dioica showed considerable antioxidant activity by inhibition of lipid peroxidation (IC50 0.83 mg/mL). The dichlormethane extract showed weak antimicrobial activity (MIC > 50 μg/mL), but slightly better activity against the yeast Candida albicans (MIC 40 μg/mL). In contrast to some previous reports, the water, methanol and ethanol extracts displayed negligible antimicrobial effects. Keywords : URTICA DIOICA, ANTIOXIDANT ACTIVITY, ANTIMICROBIAL ACTIVITY

Istanbul Medipol University