ACTA Pharmaceutica Sciencia 2020 , Vol 58 , Num 2
Chemical Composition and Anti-scabies Activity of Essential Oil of Elettaria Cardamomum Maton. Leaves
Bharat Sharma 1 Neeru Vasudeva 1 Sunil Sharma 1
1 Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar 125001, Haryana, India
DOI : 10.23893/1307-2080.APS.05812 The objective of this study was to investigate the chemical constituents of essential oil of Elettaria cardamomum leaves and assess its anti-scabies potential.

Essential oil obtained by hydrodistillation of fresh leaves of E. cardamomum, subjected to gas chromatography, gas chromatography-mass spectrometry for identification and quantification of components. Anti-scabies potential of essential oil of E. cardamomum leaves against S. scabiei was investigated by contact bioassay method.

GC and GC-MS analysis results revealed the presence of 44 compounds, representing 96.42% of the oil. The volatile components in leaves of E. cardamomum were made up of largely of oxygenated monoterpenes including terpinen-4-ol, eucalyptol, p-cymene, trans-phytol and cis-sabinene. The anti-scabies study revealed that 10% E. cardamomum oil showed 100% mortality within 60 min.

This study demonstrated the potential of E. cardamomum leaves essential oil as a scabicidal agent, therefore can be used as an alternative for the cure and effective control of S. scabiei. Keywords : Elettaria cardamomum, Essential oil, GC, GC-MS, Anti-scabies

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