ACTA Pharmaceutica Sciencia 2020 , Vol 58 , Num 1
Cytotoxic Activity of the Root and Fruit Extracts of Heptaptera Anisoptera (DC.) Tutin
Fatma Tosun 1 Mahmut Miski 2
1 Istanbul Medipol University, School of Pharmacy, Department of Pharmacognosy, Istanbul, Turkey
2 Istanbul University, Faculty of Pharmacy, Department of Pharmacognosy, Istanbul, Turkey
DOI : 10.23893/1307-2080.APS.05801 Cytotoxic activities of the root and fruit extracts of Heptaptera anisoptera (DC.) Tutin were investigated on the colon cancer COLO205 and KM12 cell lines. The dichloromethane extract of the roots of H. anisoptera showed cytotoxic activity with IC50 values of 3.1 and 3.9 ug/mL on the COLO205 and KM12 cell lines, respectively. Cytotoxic activity of the dichloromethane extract of the fruits were similar to those of root extract with IC50 values of 5.5 and 4.8 ug/mL on the COLO205 and KM12 cell lines, respectively. Keywords : Cytotoxic activity, Heptaptera anisoptera, Apiaceae

Istanbul Medipol University