ACTA Pharmaceutica Sciencia 2006 , Vol 48 , Num 1
CHARACTERIZATION OF APRICOT GUM AS A BINDER IN TABLET FORMULATIONS
D ŞENSOY, E CEVHER, T ALTINKURT
Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Technology, Istanbul, Turkey In this study, apricot gum (APG) obtained from Prunus armeniaca was evaluated as a tablet binder for wet granulation method. Tenoxicam (TNX) was chosen as the model drug. Binding property of APG was compared with other binding agents as gum arabic (GA) and polyvinyl pyrrolidone (PVP). The effect of different compression pressures on the properties of tablets was also investigated. Results indicated APG as a potential pharmaceutical binding agent when compared to GA and PVP. Keywords : PRUNUS ARMENIACA; APRICOT GUM; WET GRANULATION; TABLET BINDER; TENOXIC

Istanbul Medipol University